CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
AIH in a murine APS-1 model is directed against multiple autoantigens and can be controlled by polyspecific Tregs
DOI 10.1055/s-0032-1332135
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Hardtke-Wolenski, R Taubert, F Noyan, M Sievers, CS Falk, MS Anderson, MP Manns, E Jaeckel
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and Aims: The autoimmune polyendocrine syndrome type 1 (APS-1) is caused by genetic aberrations of the autoimmune regulator (Aire) gene and manifests as spontaneous autoimmunity against multiple organs. We planned to investigate autoimmune hepatitis (AIH) in an APS-1 reflecting mouse model. Methods: In this APS-1 model, Aire at exon 2 was truncated (Aire-Δex2) on BALB/c background. We analyzed the pathoph…
Zitieren
Zitierempfehlung
M Hardtke-Wolenski, R Taubert, F Noyan, M Sievers, CS Falk, MS Anderson, MP Manns, E Jaeckel (2013) AIH in a murine APS-1 model is directed against multiple autoantigens and can be controlled by polyspecific Tregs. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1332135
Mit CareLit weiterarbeiten