CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Genetic predisposition and environmental danger signals initiate chronic autoimmune hepatitis driven by CD4+ T cells
DOI 10.1055/s-0032-1332136
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Autor:innenM Hardtke-Wolenski, K Fischer, F Noyan, J Schlue, CS Falk, M Stahlhut, N Woller, F Kühnel, R Taubert, MP Manns, E Jaeckel
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and aims: Autoimmune hepatitis (AIH) is defined as a chronic liver disease with loss of tolerance against liver tissue eventually leading to cirrhosis if left untreated. 80–90% of patients can be treated with a life-long immunosuppression. Unfortunately there are strong drug related side effects and steroid-refractory patients. Therefore, there is a need for a model system to investigate the complex immun…
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Zitierempfehlung
M Hardtke-Wolenski, K Fischer, F Noyan, J Schlue, CS Falk, M Stahlhut, N Woller, F Kühnel, R Taubert, MP Manns, E Jaeckel (2013) Genetic predisposition and environmental danger signals initiate chronic autoimmune hepatitis driven by CD4+ T cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1332136
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