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Acetaminophen and pregnancy: increased susceptibility towards hepatotoxicity and impairment of maternal immune adaptation and fetal development

T Keßler, K Thiele, P Arck, G Tiegs · Zeitschrift für Gastroenterologie · Ausgabe 01/2013

DOI 10.1055/s-0032-1332143

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Autor:innenT Keßler, K Thiele, P Arck, G Tiegs
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben

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Objectives: Acetaminophen is used during pregnancy to treat pain or fever. Several human studies provided substantial evidence for a correlation between acetaminophen (APAP) use during pregnancy and an increased children's risk to develop asthma. We established a mouse model of APAP use during pregnancy and studied the impact of APAP on maternal liver damage and immune adaptation as well as on fetal immune developme…

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T Keßler, K Thiele, P Arck, G Tiegs (2013) Acetaminophen and pregnancy: increased susceptibility towards hepatotoxicity and impairment of maternal immune adaptation and fetal development. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1332143

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