CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Therapeutic blockade of RAGE ameliorates hepatic microcirculation in endotoxemic liver failure
DOI 10.1055/s-0032-1332149
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Autor:innenA Kuhla, J Norden, K Abshagen, B Vollmar
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Ligand binding to the receptor for advanced glycation endproducts (RAGE), which is a member of pattern-recognition-receptors (PRRs), causes sustained activation of multiple inflammatory pathways. Therefore, RAGE has potential as a new therapeutic target in sepsis. To answer if RAGE blockade could prevent hepatic microcirculatory dysfunction, being a determinant for manifestation of endotoxemic liver failure, we anal…
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Zitierempfehlung
A Kuhla, J Norden, K Abshagen, B Vollmar (2013) Therapeutic blockade of RAGE ameliorates hepatic microcirculation in endotoxemic liver failure. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1332149
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