CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Down regulation of osteopontin interferes with HCV replication by inhibition of WNT signalling in vitro
DOI 10.1055/s-0032-1332151
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Autor:innenC Loscher, R Bartenschlager, V Lohmann, G Tiegs, G Sass
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background and Aims: Osteopontin (OPN) is a secreted protein which is expressed in bone, immune cells and malignant cells. OPN is involved in migration and cell fusion and has been found upregulated in cirrhosis patients with HBV infection. We investigated relations between OPN and HCV replication as well as underlying mechanisms. Methods: For in vitro experiments the HCV replicon system expressing HCV genes NS3 to…
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Zitierempfehlung
C Loscher, R Bartenschlager, V Lohmann, G Tiegs, G Sass (2013) Down regulation of osteopontin interferes with HCV replication by inhibition of WNT signalling in vitro. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1332151
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