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Comprehensive analysis of NK cell phenotype and function during the initial phase of antiviral therapy: distinct roles of Ribavirin and Interferon alpha

AA Markova, B Bremer, U Mihm, V Schlaphoff, E Herrmann, K Stegmann, J Jaroszewicz, S Lunemann, J Grabowski, T Berg, S Zeuzem, MP Manns, M Cornberg, H Wedemeyer · Zeitschrift für Gastroenterologie · Ausgabe 01/2013

DOI 10.1055/s-0032-1332158

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Autor:innenAA Markova, B Bremer, U Mihm, V Schlaphoff, E Herrmann, K Stegmann, J Jaroszewicz, S Lunemann, J Grabowski, T Berg, S Zeuzem, MP Manns, M Cornberg, H Wedemeyer
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: Ribavirin (RBV) remains part of several interferon-free treatment strategies even though the mechanisms of action of RBV are still not fully understood. One hypothesis is that RBV increases responsiveness to type I interferons. Pegylated Interferon alpha (PEG-IFNα) has recently been shown to alter phenotype and function of NK cells which correlates with control of HCV infection. However, the effects of r…

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AA Markova, B Bremer, U Mihm, V Schlaphoff, E Herrmann, K Stegmann, J Jaroszewicz, S Lunemann, J Grabowski, T Berg, S Zeuzem, MP Manns, M Cornberg, H Wedemeyer (2013) Comprehensive analysis of NK cell phenotype and function during the initial phase of antiviral therapy: distinct roles of Ribavirin and Interferon alpha. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1332158

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