CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Accelerated but transient generation of cytotoxic T cells by cross-presenting liver sinusoidal endothelial cells
DOI 10.1055/s-0032-1332174
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Autor:innenO Schanz, JP Böttcher, A Zaremba, S Hegenbarth, PA Knolle
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Liver sinusoidal endothelial cells (LSEC), the most abundant non-parenchymal cell population in the liver, efficiently take up soluble antigens coming from the intestinal tract and the systemic circulation. LSEC cross-present these antigens to CD8 T cells, thereby inducing non-functional memory-like CD8 T cells under non-inflammatory conditions. Here we compared the early steps of CD8 T cell priming by LSEC to class…
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Zitierempfehlung
O Schanz, JP Böttcher, A Zaremba, S Hegenbarth, PA Knolle (2013) Accelerated but transient generation of cytotoxic T cells by cross-presenting liver sinusoidal endothelial cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0032-1332174
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