CareLit · DOI-Nachweis · Pneumologie
Mast cells and fibroblasts work in concert to aggravate pulmonary fibrosis: role of transmembrane stem cell factor (SCF) and PAR-2/PKCalpha/Raf-1/p44/42 signaling pathway
DOI 10.1055/s-0033-1334523
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Wygrecka, B Dahal, D Kosanovic, F Petersen, B Taborski, KT Preissner, RT Schermuly, P Markart
ZeitschriftPneumologie
Ausgabe02/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Mast cell (MC) accumulation has been demonstrated in the lungs of idiopathic pulmonary fibrosis (IPF) patients. Mediators released from MCs may regulate tissue remodelling processes, thereby contributing to IPF pathogenesis. In this study, we investigated the role of MC-fibroblast interaction for the progression of lung fibrosis. We observed increased number of activated MCs in IPF lungs, located in close proximity…
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Zitierempfehlung
M Wygrecka, B Dahal, D Kosanovic, F Petersen, B Taborski, KT Preissner, RT Schermuly, P Markart (2013) Mast cells and fibroblasts work in concert to aggravate pulmonary fibrosis: role of transmembrane stem cell factor (SCF) and PAR-2/PKCalpha/Raf-1/p44/42 signaling pathway. Pneumologie (02). https://doi.org/10.1055/s-0033-1334523
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