CareLit · DOI-Nachweis · Zeitschrift für Phytotherapie
Investigations into the bioactive constituents of hawthorn extract WS® 1442 responsible for its endothelial barrier protecting activity
DOI 10.1055/s-0033-1338198
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Autor:innenS Fuchs, EA Willer, E Hartung, AM Vollmar, O Potterat, M Hamburger, R Fürst
ZeitschriftZeitschrift für Phytotherapie
Ausgabe03/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
We could previously prove that WS® 1442, a herbal drug approved against mild forms of heart failure, efficiently prevents inflammation-induced endothelial hyperpermeability in vitro and in vivo by blocking the Ca2+/PKC/RhoA pathway and by activating cAMP/Rap1/Rac1 signaling [1]. In the search for the constituents responsible for these effects, we previously examined 4 different fractions (A-D) of WS® 1442 (Sephadex…
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Zitierempfehlung
S Fuchs, EA Willer, E Hartung, AM Vollmar, O Potterat, M Hamburger, R Fürst (2013) Investigations into the bioactive constituents of hawthorn extract WS® 1442 responsible for its endothelial barrier protecting activity. Zeitschrift für Phytotherapie (03). https://doi.org/10.1055/s-0033-1338198
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