CareLit · DOI-Nachweis · Zeitschrift für Phytotherapie
Isolation and investigation of potassium channel activity of Aconitum diterpene alkaloids
DOI 10.1055/s-0033-1338200
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Autor:innenT Kiss, D Csupor, P Orvos, L Tálosi, J Hohmann
ZeitschriftZeitschrift für Phytotherapie
Ausgabe03/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Diterpene alkaloids isolated from Aconitum species exert activity on Na+ and K+ channels thus these compounds have strong cardiac effects. Depending on skeletal types and substitution patterns the binding affinity may be diverse. The majority of Aconitum alkaloids may cause arrhythmia and heart arrest by the activation of voltage-dependent Na+ channels. Others act as competitive antagonist of the arrhyth…
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Zitierempfehlung
T Kiss, D Csupor, P Orvos, L Tálosi, J Hohmann (2013) Isolation and investigation of potassium channel activity of Aconitum diterpene alkaloids. Zeitschrift für Phytotherapie (03). https://doi.org/10.1055/s-0033-1338200
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