CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
p8 is a novel intracellular mediator of pancreatic beta cell protection that preserves insulin secretory function during inflammatory stress in vivo
DOI 10.1055/s-0033-1341712
Bibliografische Angaben
Nachweis in CareLit
Autor:innenAE Mehana, I Pilz, B Dufner, C Jäger, S Sojka, J Baumann, M Alt, C Liu, N Perakakis, K Laubner, G Päth, J Seufert
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2013
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: A current hypothesis considers type 2 diabetes as a result of over nutrition-induced local inflammation leading to insulin resistance, insulin secretory dysfunction and finally pancreatic beta cell loss. The intracellular protein p8 has been shown to reduce tissue damage during acute pancreatitis. To investigate its role in the endocrine pancreas we generated transgenic mice with beta cell-specific p8…
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Zitierempfehlung
AE Mehana, I Pilz, B Dufner, C Jäger, S Sojka, J Baumann, M Alt, C Liu, N Perakakis, K Laubner, G Päth, J Seufert (2013) p8 is a novel intracellular mediator of pancreatic beta cell protection that preserves insulin secretory function during inflammatory stress in vivo. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0033-1341712
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