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Efficacy and safety of Canagliflozin (CANA), an inhibitor of Sodium Glucose Co-Transporter 2 (SGLT2), added on to insulin therapy with or without oral agents in type 2 diabetes (T2D)

D Matthews, G Fulcher, V Perkovic, D de Zeeuw, KW Mahaffey, J Rosenstock, M Davies, G Capuano, M Desai, W Shaw, F Vercruysse, G Meininger, B Neal · Diabetologie und Stoffwechsel · Ausgabe 04/2013

DOI 10.1055/s-0033-1341911

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Autor:innenD Matthews, G Fulcher, V Perkovic, D de Zeeuw, KW Mahaffey, J Rosenstock, M Davies, G Capuano, M Desai, W Shaw, F Vercruysse, G Meininger, B Neal
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2013
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Question: SGLT2 inhibition is a novel treatment modality for T2D. We report here a pre-specified substudy of the CANagliflozin cardioVascular Assessment Study (CANVAS) defining the efficacy and safety of CANA in subjects with T2D on insulin. Methodology: CANVAS is a double-blind, placebo (PBO)-controlled study that randomized 4,330 individuals at elevated cardiovascular risk to the addition of CANA 100 or 300 mg or…

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Zitierempfehlung

D Matthews, G Fulcher, V Perkovic, D de Zeeuw, KW Mahaffey, J Rosenstock, M Davies, G Capuano, M Desai, W Shaw, F Vercruysse, G Meininger, B Neal (2013) Efficacy and safety of Canagliflozin (CANA), an inhibitor of Sodium Glucose Co-Transporter 2 (SGLT2), added on to insulin therapy with or without oral agents in type 2 diabetes (T2D). Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0033-1341911

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