CareLit · DOI-Nachweis · Klinische Pädiatrie
Darwinian Fitness of Acute Lymphoblastic Leukaemia
DOI 10.1055/s-0033-1343626
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Nachweis in CareLit
Autor:innenK Dormon, J Vormoor, O Heidenreich
ZeitschriftKlinische Pädiatrie
Ausgabe05/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Clinically, relapsed ALL is characterized by a very poor treatment response and is, thus, considered to be more aggressive. We have competitively transplanted matched presentation and relapse material derived from a t(17;19) ALL. Relapse cells were discriminated from presentation cells by a 5q deletion of 5 genes (NR3C1, HMHB1, ARHGAP26, FGF1 and YIPF5). Surprisingly, presentation cells always outcompeted relapse ce…
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Zitierempfehlung
K Dormon, J Vormoor, O Heidenreich (2013) Darwinian Fitness of Acute Lymphoblastic Leukaemia. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0033-1343626
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