CareLit · DOI-Nachweis · Klinische Pädiatrie
Prognostic relevance of disordered epigenetic regulation in juvenile myelomonocytic leukemia
DOI 10.1055/s-0033-1343633
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Fluhr, T Witte, CF Krombholz, C Plass, CM Niemeyer, C Flotho
ZeitschriftKlinische Pädiatrie
Ausgabe05/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Juvenile myelomonocytic leukemia (JMML) is a myeloproliferative disorder of early childhood which takes a fatal course in most cases unless treated with hematopoietic stem cell transplantation. We recently provided evidence for epigenetic dysregulation in JMML and showed that aberrant DNA methylation at defined loci strongly correlates with disease progression and outcome. We have now extended the methylation analys…
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Zitierempfehlung
S Fluhr, T Witte, CF Krombholz, C Plass, CM Niemeyer, C Flotho (2013) Prognostic relevance of disordered epigenetic regulation in juvenile myelomonocytic leukemia. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0033-1343633
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