CareLit · DOI-Nachweis · Klinische Pädiatrie
p38α/β inhibition prevents ALL proliferation in vivo
DOI 10.1055/s-0033-1343634
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Autor:innenS Strube, S Krause, M Stanulla, M Schrappe, D Schewe
ZeitschriftKlinische Pädiatrie
Ausgabe05/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
P38α/β stress-activated protein kinase has been described as an important regulator of dormancy and tumor cell dissemination in different epithelial malignancies. However, p38α/β also regulates other cellular processes such as inflammation, apoptosis and, rarely, cell cycle progression. Here, we study the role of p38α/β as a targetable mediator of acute lymphoblastic leukemia (ALL) proliferation. P38α/β was highly p…
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Zitierempfehlung
S Strube, S Krause, M Stanulla, M Schrappe, D Schewe (2013) p38α/β inhibition prevents ALL proliferation in vivo. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0033-1343634
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