CareLit · DOI-Nachweis · Klinische Pädiatrie
Generation and characterization of ganglidiximab for active immunotherapy of neuroblastoma
DOI 10.1055/s-0033-1343643
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Nachweis in CareLit
Autor:innenC Eger, D Brackrock, N Siebert, HN Lode
ZeitschriftKlinische Pädiatrie
Ausgabe05/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Ganglidiomab is a murine IgG1 anti-idiotype antibody of anti-GD2 Ab ch14.18. We previously demonstrated an active GD2-specific humoral immune response against neuroblastoma (NB) after immunization of mice with ganglidiomab. To tailor this response to the murine variable regions in humans and to minimize nonspecific response against murine constant regions, we exchanged murine with human constant region…
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Zitierempfehlung
C Eger, D Brackrock, N Siebert, HN Lode (2013) Generation and characterization of ganglidiximab for active immunotherapy of neuroblastoma. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0033-1343643
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