CareLit · DOI-Nachweis · Klinische Pädiatrie
Dysregulated expression of histone deacetylases in medulloblastoma – potential targets for selective inhibitor treatment
DOI 10.1055/s-0033-1343647
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Ecker, I Oehme, A Schomburg, R Mazitschek, A Korshunov, M Kool, HE Deubzer, A von Deimling, AE Kulozik, S Pfister, O Witt, T Milde
ZeitschriftKlinische Pädiatrie
Ausgabe05/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Medulloblastoma is the most common malignant brain tumor in childhood comprising 4 molecular subgroups. Survival rates remain particularly poor for patients with subgroup 3 tumors despite multimodal treatment. Therefore targeted therapies are urgently needed. Broad-spectrum inhibition of histone deacetylases (HDACs) has previously been shown to be a promising approach in cancer therapy. We here explore…
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Zitierempfehlung
J Ecker, I Oehme, A Schomburg, R Mazitschek, A Korshunov, M Kool, HE Deubzer, A von Deimling, AE Kulozik, S Pfister, O Witt, T Milde (2013) Dysregulated expression of histone deacetylases in medulloblastoma – potential targets for selective inhibitor treatment. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0033-1343647
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