CareLit · DOI-Nachweis · Klinische Pädiatrie
MYCN amplification predicts poor outcome of patients with LIN28 negative supratentorial primitive neuroectodermal tumors of the central nervous system (CNS-PNET)
DOI 10.1055/s-0033-1343648
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Nachweis in CareLit
Autor:innenM Gessi, A von Büren, A Treitzl, A zur Mühlen, S Rutkowski, T Pietsch
ZeitschriftKlinische Pädiatrie
Ausgabe05/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Primitive neuroectodermal tumors of the central nervous system (CNS-PNET) are rare neoplasms. Whereas ependymoblastomas frequently carry chr. 19q13.41 amplifications, express the stem cell marker LIN28 and show aggressive clinical behaviour, the biology of other supratentorial CNS-PNETs remains so far poorly understood and prognostic genetic alterations suitable for molecular risk stratification are to date not defi…
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Zitierempfehlung
M Gessi, A von Büren, A Treitzl, A zur Mühlen, S Rutkowski, T Pietsch (2013) MYCN amplification predicts poor outcome of patients with LIN28 negative supratentorial primitive neuroectodermal tumors of the central nervous system (CNS-PNET). Klinische Pädiatrie (05). https://doi.org/10.1055/s-0033-1343648
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