CareLit · DOI-Nachweis · Klinische Pädiatrie
Establishing novel test systems to functionally analyze direct and reciprocal MLL fusion proteins
DOI 10.1055/s-0033-1343652
Bibliografische Angaben
Nachweis in CareLit
Autor:innenK Karl, E Kowarz, T Dingermann, R Marschalek
ZeitschriftKlinische Pädiatrie
Ausgabe05/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
We have set up a series of sleeping beauty vector systems that allow us to quickly analyze direct and reciprocal MLL fusions by cloning only the corresponding partner cDNAs. Here we present first data cellular properties exerted by MLL-MAML2, MAML2-MLL, MLL-NEBL, NEBL-MLL, MLL-LASP1 and LASP2-MLL. All fusion genes were either tested alone or in combination. Stable cell lines were established and proper integration a…
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Zitierempfehlung
K Karl, E Kowarz, T Dingermann, R Marschalek (2013) Establishing novel test systems to functionally analyze direct and reciprocal MLL fusion proteins. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0033-1343652
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