CareLit · DOI-Nachweis · Klinische Pädiatrie
Development of dual function MYCN-DNA vaccines for anti-neuroblastoma immunotherapy
DOI 10.1055/s-0033-1343655
Bibliografische Angaben
Nachweis in CareLit
Autor:innenD Reker, A Stermann, N Huebener, N Siebert, HN Lode
ZeitschriftKlinische Pädiatrie
Ausgabe05/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: We recently showed that MYCN-DNA minigene vaccination is an effective immunotherapeutic approach to treat MYCN-amplified neuroblastoma (NB) in vivo. To further enhance the therapeutic efficacy, we designed dual function DNA-vaccines driving the expression of MYCN antigens and interleukins (ILs) such as IL-2, IL-15 and IL-21 in one vector. Methods/Results: For this purpose, previously established MYCN m…
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Zitierempfehlung
D Reker, A Stermann, N Huebener, N Siebert, HN Lode (2013) Development of dual function MYCN-DNA vaccines for anti-neuroblastoma immunotherapy. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0033-1343655
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