CareLit · DOI-Nachweis · Klinische Pädiatrie
Delineation of protein networks affected by somatic mutation in neuroblastoma
DOI 10.1055/s-0033-1343660
Bibliografische Angaben
Nachweis in CareLit
Autor:innenF Roels, M Peifer, B Hero, F Berthold, M Fischer
ZeitschriftKlinische Pädiatrie
Ausgabe05/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aim:The mutational spectrum of neuroblastoma is highly heterogeneous. Here, we aim to delineate protein interaction networks that are recurrently affected by somatic mutations in neuroblastoma using whole exome sequencing. Method: Using the concepts of network hierarchy and modularity, we developed a novel similarity metric to compare pairs of genes. The metric incorporates information about the structure of the pro…
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Zitierempfehlung
F Roels, M Peifer, B Hero, F Berthold, M Fischer (2013) Delineation of protein networks affected by somatic mutation in neuroblastoma. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0033-1343660
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