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Development of an innovative 3D cell culture system to study tumour – stroma interactions in non-small cell lung cancer cells

A Amann, M Zwierzina, G Gamerith, M Bitsche, J Huber, G Vogel, M Blumer, J Kelm, W Hilbe, H Zwierzina · Pneumologie · Ausgabe 05/2013

DOI 10.1055/s-0033-1345039

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Autor:innenA Amann, M Zwierzina, G Gamerith, M Bitsche, J Huber, G Vogel, M Blumer, J Kelm, W Hilbe, H Zwierzina
ZeitschriftPneumologie
Ausgabe05/2013
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Introduction: We describe a novel 3D co-culture method using non-small cell lung cancer (NSCLC) cell lines in combination with a lung fibroblast cell line in the hanging drop technology. Compared to other 3D models, it better reflects tumour growth in its microenvironment since no addition of growth factors or artificial extracellular matrix (ECM) substitutes are required. Methods: Automation-compatible multi-well h…

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Zitierempfehlung

A Amann, M Zwierzina, G Gamerith, M Bitsche, J Huber, G Vogel, M Blumer, J Kelm, W Hilbe, H Zwierzina (2013) Development of an innovative 3D cell culture system to study tumour – stroma interactions in non-small cell lung cancer cells. Pneumologie (05). https://doi.org/10.1055/s-0033-1345039

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