CareLit · DOI-Nachweis · Pneumologie
Role of JAK-STAT pathway in pulmonary fibrosis
DOI 10.1055/s-0033-1345044
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Eschenbrenner, W Janssen, B Kojonazarov, K Murmann, A Ghofrani, N Weissmann, F Grimminger, W Seeger, RT Schermuly
ZeitschriftPneumologie
Ausgabe05/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Rationale: Prior studies suggested a constitutive activation of Signal Transducer and Activator of Transcription 3 (STAT3) in pulmonary fibrosis. STAT3 is part of the Janus Kinase (JAK)-STAT pathway, which is important for developmental regulation, growth control, and hemostasis in multicellular organisms. Several mediators like Interleukin (IL)-4 and Il-13, and factors like Platelet Derived Growth Factor (PDGF), th…
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Zitierempfehlung
J Eschenbrenner, W Janssen, B Kojonazarov, K Murmann, A Ghofrani, N Weissmann, F Grimminger, W Seeger, RT Schermuly (2013) Role of JAK-STAT pathway in pulmonary fibrosis. Pneumologie (05). https://doi.org/10.1055/s-0033-1345044
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