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Using field accelerated plasmid droplets (electrospray) for transfection into pulmonary tissue: An approach towards bronchoscopic-based gene therapy

A Gazdhar, S Boehringer, D Hradetzky, T Geiser · Pneumologie · Ausgabe 05/2013

DOI 10.1055/s-0033-1345045

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Autor:innenA Gazdhar, S Boehringer, D Hradetzky, T Geiser
ZeitschriftPneumologie
Ausgabe05/2013
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: Gene therapy is a promising approach for lung diseases however a major challenge is the delivery of the substances into specific cells. For therapeutic application the delivery mechanism has to be transferred into suitable delivery and device concept useable within the working channel of a bronchoscope. Here we present our concept and first results of electrospray device on cell culture and ex-vivo lung…

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A Gazdhar, S Boehringer, D Hradetzky, T Geiser (2013) Using field accelerated plasmid droplets (electrospray) for transfection into pulmonary tissue: An approach towards bronchoscopic-based gene therapy. Pneumologie (05). https://doi.org/10.1055/s-0033-1345045

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