CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Myofibroblast-derived secreted frizzled-related protein 1 (SFRP1) can inhibit colorectal carcinoma field cancerization
DOI 10.1055/s-0033-1347529
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Autor:innenG Valcz, V Patai, I Füri, A Kalmár, B Péterfia, F Sipos, T Krenács, N Nagy, G Barna, B Wichmann, B Molnár, Z Tulassay
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Despite frequent mutations of canonical Wnt signal in colorectal cancer (CRC), the α-SMA+ myofibroblast-derived interellular Wnt regulator SFRP1 may play a crucial role in the inhibiton of autocrine Wnt loop in epithelial cells. This effect may appear in the genetically and epigenetically altered, but histologically normal adjacent tumor (NAT) areas and inhibit field cancerization. Aims: We compared the…
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Zitierempfehlung
G Valcz, V Patai, I Füri, A Kalmár, B Péterfia, F Sipos, T Krenács, N Nagy, G Barna, B Wichmann, B Molnár, Z Tulassay (2013) Myofibroblast-derived secreted frizzled-related protein 1 (SFRP1) can inhibit colorectal carcinoma field cancerization. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-0033-1347529
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