CareLit · DOI-Nachweis · Senologie - Zeitschrift für Mammadiagnostik und -therapie
EMT transcription factor ZEB1 regulates the epigenetic repression of the miRNA-141/200c cluster during EMT in breast cancer
DOI 10.1055/s-0033-1347647
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Autor:innenRP Neves, M Uhrberg, N Stöcklein, T Fehm, D Niederacher
ZeitschriftSenologie - Zeitschrift für Mammadiagnostik und -therapie
Ausgabe06/2013
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Objectives: ZEB1 has a central role during epithelial-to-mesenchymal transition (EMT) repressing several genes like the miR-200 family of miRNAs. We previously identified miR-200c and miR-141, two members of that family, as being silenced also by DNA methylation on mesenchymal-like breast cancer cells. Since it is not known how or if these two repressive mechanisms (ZEB1 and DNA methylation) coordinate to silence th…
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Zitierempfehlung
RP Neves, M Uhrberg, N Stöcklein, T Fehm, D Niederacher (2013) EMT transcription factor ZEB1 regulates the epigenetic repression of the miRNA-141/200c cluster during EMT in breast cancer. Senologie - Zeitschrift für Mammadiagnostik und -therapie (06). https://doi.org/10.1055/s-0033-1347647
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