CareLit · DOI-Nachweis · Geburtshilfe und Frauenheilkunde
Heparin Strongly Induces Soluble Fms-Like Tyrosine Kinase 1 (sFlt1) Release in vivo and in vitro
DOI 10.1055/s-0033-1347752
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Nachweis in CareLit
Autor:innenF Herse, J Searle, JO Vollert, A Slagman, C Mueller, DN Müller, M Möckel, R Dechend
ZeitschriftGeburtshilfe und Frauenheilkunde
Ausgabe06/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Soluble fms-like tyrosine kinase 1 (sFlt1) is involved in preeclampsia and coro- nary artery disease, which share endothelial dysfunction in common. Since sFlt1 has a major heparin-binding site, we aimed to prove that sFlt1, which is “stored” by heparan sulphate proteoglycans on the cell surface and/or in the extracellular matrix, is released upon heparin administration due to a competitive mechanism. Me…
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Zitierempfehlung
F Herse, J Searle, JO Vollert, A Slagman, C Mueller, DN Müller, M Möckel, R Dechend (2013) Heparin Strongly Induces Soluble Fms-Like Tyrosine Kinase 1 (sFlt1) Release in vivo and in vitro. Geburtshilfe und Frauenheilkunde (06). https://doi.org/10.1055/s-0033-1347752
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