CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Inhibition of GTP cyclohydrolase enhances intestinal inflammation in mice
DOI 10.1055/s-0033-1352655
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Nachweis in CareLit
Autor:innenG Pickert, I Tegeder, D Schuppan
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and aims: GTP cyclohydrolase (GCH1) is the rate-limiting enzyme for tetrahydrobiopterin (BH4) synthesis which is an essential cofactor for catecholamine, serotonin and nitric oxide production. GCH1 is a key modulator of peripheral neuropathic and inflammatory pain. However, the role of GCH1 in the intestinal inflammation is not well understood. Methods and results: We studied the role of GCH1 by using the…
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Zitierempfehlung
G Pickert, I Tegeder, D Schuppan (2013) Inhibition of GTP cyclohydrolase enhances intestinal inflammation in mice. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0033-1352655
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