CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Kinome-wide RNAi screen identifies key role of dual specificity kinase Mps1 in proliferation and survival of pancreatic cancer cells
DOI 10.1055/s-0033-1352691
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Nachweis in CareLit
Autor:innenBP Kaistha, T Honstein, VP Müller, C Schmees, HJ Volkmer, TM Gress, M Buchholz
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related deaths in the western world. Currently it is incurable with existing therapies. The median survival rate (˜6 months) and the overall 5-year survival rate (< 5%) has not improved despite significant research and diagnostic efforts, warranting the urgent need for novel therapeutic targets and approaches. Protein kinases…
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Zitierempfehlung
BP Kaistha, T Honstein, VP Müller, C Schmees, HJ Volkmer, TM Gress, M Buchholz (2013) Kinome-wide RNAi screen identifies key role of dual specificity kinase Mps1 in proliferation and survival of pancreatic cancer cells. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0033-1352691
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