CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Blockade of PDGFR family together with SRC leads to diminished proliferation of CRC cells
DOI 10.1055/s-0033-1352700
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Autor:innenS Kaulfuß, H Seemann, R Kampe, J Meyer, R Dressel, B König, JG Scharf, P Burfeind
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Among the family of receptor tyrosine kinases (RTKs) the platelet-derived growth factor receptor (PDGFR) has attracted increasing attention as potential target of anti-tumor therapy in colorectal cancer (CRC). Methods/Results: Varying expression of the PDGFRβ was demonstrated in CRC cell lines. SW480 cells showing the highest PDGFRβ expression were used for receptor down-regulation by siRNA and by the pharmaco…
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Zitierempfehlung
S Kaulfuß, H Seemann, R Kampe, J Meyer, R Dressel, B König, JG Scharf, P Burfeind (2013) Blockade of PDGFR family together with SRC leads to diminished proliferation of CRC cells. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0033-1352700
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