CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
“Pulsed” versus “continuous” application of the prodrug 5-FC for enhancing oncolytic effectiveness of a measles vaccine virus armed with a suicide gene
DOI 10.1055/s-0033-1352706
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Autor:innenC Yurttas, S Berchtold, NP Malek, M Bitzer, UM Lauer
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Oncolytic virotherapy with measles vaccine virus (MeV) has already been demonstrated to be safe (Galanis et al., 2010). However, when monitoring the expression of the MeV encoded reporter gene CEA it was found (i) that only few tumor cells were infected by MeV and (ii) that subsequently to initial tumor colonization no substantial production of progeny MeV particles took place in the respective cancer patients (Russ…
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Zitierempfehlung
C Yurttas, S Berchtold, NP Malek, M Bitzer, UM Lauer (2013) “Pulsed” versus “continuous” application of the prodrug 5-FC for enhancing oncolytic effectiveness of a measles vaccine virus armed with a suicide gene. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0033-1352706
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