CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
KRAS mutations influence the cellular behavior and response of CRC cells to a 5-Fluorouracil (FU) based radiochemotherapy combined with receptor tyrosine kinase inhibitors
DOI 10.1055/s-0033-1352709
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Autor:innenS Wiedmann, J Gaedcke, M Rave-Fränk, JG Scharf, P Burfeind, S Kaulfuß
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Mutations of the proto-oncogene KRAS are supposed to lead to an increased activity of KRAS inducing a constitutive activation of the downstream MAPK signaling pathway. The aim of the work was to investigate the behavior of colorectal cancer cell line SW 480 with different mutations in KRAS and their response to a combined radiochemotherapy (RCT) in the absence or presence of different receptor tyrosine kinase…
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Zitierempfehlung
S Wiedmann, J Gaedcke, M Rave-Fränk, JG Scharf, P Burfeind, S Kaulfuß (2013) KRAS mutations influence the cellular behavior and response of CRC cells to a 5-Fluorouracil (FU) based radiochemotherapy combined with receptor tyrosine kinase inhibitors. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0033-1352709
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