CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Glucose transporter isoform 1 (GLUT1) expression in melanoma enhances formation and growth of hepatic metastases
DOI 10.1055/s-0033-1352713
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Autor:innenA Koch, P Wild, M Kreutz, M Müller, A Bosserhoff, C Hellerbrand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
GLUT1 is the key rate-limiting factor in glucose transport into cancer cells. We aimed to analyze whether GLUT1 expression in cancer cells and a high capacity for glucose uptake, respectively, affect hepatic metastasis. For that, we used malignant melanoma as a model-tumor, which is known to preferentially metastasize to the liver. Methods and Results: Similar as observed in HCC, GLUT1 expression was enhanced in mel…
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Zitierempfehlung
A Koch, P Wild, M Kreutz, M Müller, A Bosserhoff, C Hellerbrand (2013) Glucose transporter isoform 1 (GLUT1) expression in melanoma enhances formation and growth of hepatic metastases. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0033-1352713
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