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MeV-RII_HepG2, a persistently measles virus (MeV) infected human hepatoma cell line, displays resistance towards secondary infections with MeV virotherapeutics

S Berchtold, T Weiland, J Lampe, I Smirnow, S Venturelli, A Berger, J Reiser, F Stubenrauch, NP Malek, M Bitzer, UM Lauer · Zeitschrift für Gastroenterologie · Ausgabe 08/2013

DOI 10.1055/s-0033-1352728

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Autor:innenS Berchtold, T Weiland, J Lampe, I Smirnow, S Venturelli, A Berger, J Reiser, F Stubenrauch, NP Malek, M Bitzer, UM Lauer
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2013
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Introduction: The oncolytic potential of measles vaccine virus (MeV) has been shown both in vitro and in vivo. On the contrary, resistances to MeV-mediated oncolysis were demonstrated to either pre-exist or arise in the course of MeV virotherapy. To investigate mechanisms of secondary resistance we have generated a hepatoma cell line being persistently infected with MeV (MeV-RII_HepG2) which was generated by two rou…

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S Berchtold, T Weiland, J Lampe, I Smirnow, S Venturelli, A Berger, J Reiser, F Stubenrauch, NP Malek, M Bitzer, UM Lauer (2013) MeV-RII_HepG2, a persistently measles virus (MeV) infected human hepatoma cell line, displays resistance towards secondary infections with MeV virotherapeutics. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0033-1352728

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