CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Histological hepatocyte damage precedes steatosis in ALD patients with genetic variant l148 M in PNPLA3
DOI 10.1055/s-0033-1352758
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Autor:innenV Rausch, T Peccerella, HK Seitz, F Stickel, E Yagmur, S Herzig, S Mueller
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2013
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aim: The non-synonymous single nucleotide polymorphism rs738409C->G in PNPLA3 that substitutes methionine for isoleucine at residue 148 (I148 M) has been identified as major genetic confounding factor of liver steatosis and fibrosis progression both in patients with alcoholic and non-alcoholic liver disease (ALD and NAFLD). Since the PNPLA3 function remains largely unknown, we here studied in detail sub-histological…
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Zitierempfehlung
V Rausch, T Peccerella, HK Seitz, F Stickel, E Yagmur, S Herzig, S Mueller (2013) Histological hepatocyte damage precedes steatosis in ALD patients with genetic variant l148 M in PNPLA3. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0033-1352758
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