CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Anti-inflammatory and direct antifibrotic effect of the oral hepatotropic DPP4 inhibitor Linagliptin in model of bilary fibrosis and NASH
DOI 10.1055/s-0033-1352814
Bibliografische Angaben
Nachweis in CareLit
Autor:innenXY Wang, SY Weng, T Klein, YO Kim, D Schuppan
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and aims: Non-alcoholic steatohepatitis (NASH) ischaracterized by steatosis, lobular inflammation and progressive pericellular fibrosis. Anti-inflammatory and especially antifibrotic therapies for NASH are urgently needed. The incretin glucagon like peptide 1 (GLP-1) is rapidly inactivated by dipeptidyl peptidase-4 (DPP-4), an enzyme produced by various cells, including intestinal epithelia and hepatocyte…
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Zitierempfehlung
XY Wang, SY Weng, T Klein, YO Kim, D Schuppan (2013) Anti-inflammatory and direct antifibrotic effect of the oral hepatotropic DPP4 inhibitor Linagliptin in model of bilary fibrosis and NASH. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0033-1352814
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