CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Antidromic NFATc1 and p53 signaling at the edge of differentiation and stemness in pancreatic cancer
DOI 10.1055/s-0033-1352849
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Autor:innenSK Singh, S Vogt, N Völker, B Geisel, NM Chen, E Glesel, K Reutlinger, G Singh, S Baumgart, TM Gress, V Ellenrieder
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2013
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: The current concept suggests a direct link between EMT and stemness induction in pancreatic cancer, thereby coupling cell motility and de-differentiation with self-renewal capacities and drug resistance. Both key features of cellular plasticity are controlled by distinct intracellular signaling and transcription pathways. We have shown that activation of the NFATc1 transcription factor promotes pancrea…
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Zitierempfehlung
SK Singh, S Vogt, N Völker, B Geisel, NM Chen, E Glesel, K Reutlinger, G Singh, S Baumgart, TM Gress, V Ellenrieder (2013) Antidromic NFATc1 and p53 signaling at the edge of differentiation and stemness in pancreatic cancer. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0033-1352849
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