CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Protein Kinase D2 (PKD2) controls pancreatic cancer cell invasion and angiogenesis by secretion of trypsins PRSS1 and 3 as well as matrix-metalloproteases
DOI 10.1055/s-0033-1352866
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Nachweis in CareLit
Autor:innenT Eiseler, C Wille, C Köhler, T Seufferlein
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The elucidation of signaling pathways controlling pancreatic cancer cell invasion and angiogenesis is pivotal to control and develop strategies against metastasis. Protein Kinase D2 (PKD2) is strongly expressed in pancreatic cancer cells. It is a key regulator of trypsin (PRSS1, PRSS3) as well as matrix-metalloprotease 7 and 9 (MMP 7 and 9) expression and secretion. PRSS1 and 3 are involved in cleavage of surface pr…
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Zitierempfehlung
T Eiseler, C Wille, C Köhler, T Seufferlein (2013) Protein Kinase D2 (PKD2) controls pancreatic cancer cell invasion and angiogenesis by secretion of trypsins PRSS1 and 3 as well as matrix-metalloproteases. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0033-1352866
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