CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The development of fibrosis in a novel model of chronic pancreatitis is mediated by complement factor C5
DOI 10.1055/s-0033-1352868
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Autor:innenM Sendler, G Beyer, V Kauschke, S Maertin, T Wartmann, FU Weiß, W Halangk, MM Lerch, J Mayerle
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2013
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aim: Chronic pancreatitis is accompanied with the loss of exocrine function and the development of fibrosis. We investigate the effect of complement factor 5 (C5) in a newly established murine model of chronic pancreatitis and compared it to repetitive caerulein injections. Methods: Chronic pancreatitis was induced in C5+/+ and C5–/– mice by ligation of the pancreatic duct in the body of the organ (leaving the pancr…
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Zitierempfehlung
M Sendler, G Beyer, V Kauschke, S Maertin, T Wartmann, FU Weiß, W Halangk, MM Lerch, J Mayerle (2013) The development of fibrosis in a novel model of chronic pancreatitis is mediated by complement factor C5. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0033-1352868
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