CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Overexpression of heat-shock protein 27 (HSP27) increases gemcitabine sensitivity in human pancreatic cancer cells through cell cycle arrest and apoptosis
DOI 10.1055/s-0033-1352869
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Nachweis in CareLit
Autor:innenY Guo, A Ziesch, EN De Toni, E Gallmeier
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2013
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: We previously established a role for HSP27 as a prognostic and predictive marker in pancreatic cancer: Tissue-microarray studies showed increased HSP27 expression in pancreatic cancer specimens to be associated with better patient survival, while HSP27 overexpression unexpectedly increased susceptibility specifically towards gemcitabine in a pancreatic cancer cell line model. Purpose: To further elucidate the…
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Zitierempfehlung
Y Guo, A Ziesch, EN De Toni, E Gallmeier (2013) Overexpression of heat-shock protein 27 (HSP27) increases gemcitabine sensitivity in human pancreatic cancer cells through cell cycle arrest and apoptosis. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0033-1352869
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