CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Alpha-1-Antitrypsin inhibits acute liver failure in mice
DOI 10.1055/s-0033-1360846
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Autor:innenN Jedicke, N Struever, N Aggarwal, T Welte, MP Michael, N Malek, L Zender, S Janciauskiene, T Wuestefeld
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Acute liver failure remains a critical clinical condition with high mortality rates, and increased apoptosis of hepatocytes represents a key event in the cause of liver failure. Alpha-1-Antitrypsin (AAT) is synthesized and secreted mainly by hepatocytes, and plasma purified AAT is used for augmentation therapy in patients with AAT deficiency. Because AAT therapy exerts anti-inflammatory and immune modulatory activit…
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Zitierempfehlung
N Jedicke, N Struever, N Aggarwal, T Welte, MP Michael, N Malek, L Zender, S Janciauskiene, T Wuestefeld (2014) Alpha-1-Antitrypsin inhibits acute liver failure in mice. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1360846
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