CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Blockade of NLRP3 expression in primary hepatocytes by inhibitors of NF-κB signalling
DOI 10.1055/s-0033-1360850
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Autor:innenSG Boaru, E Borkham-Kamphorst, R Weiskirchen
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The activation of NLRP3 inflammasome is performed in two steps. In a first step pro-inflammatory cytokines such as interleukin-1β (IL-1β) become activated by proteolytic cleavage of their proforms. As a consequence they stimulate the assembly of the NLRP3 inflammasome representing a large cytoplasmic multiprotein complex that process a large variety of danger and stress signals that are triggered by lipopolysacchari…
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Zitierempfehlung
SG Boaru, E Borkham-Kamphorst, R Weiskirchen (2014) Blockade of NLRP3 expression in primary hepatocytes by inhibitors of NF-κB signalling. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1360850
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