CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Expression and function of glucose transporter 1 (GLUT1) expression in activated hepatic stellate cells
DOI 10.1055/s-0033-1360859
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Autor:innenB Czech, D Valletta, M Müller, A Bosserhoff, C Hellerbrand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Hyperglycemia is one of the factors known to induce and promote hepatic fibrogenesis, however, glucose metabolism in activated hepatic stellate cells (HSCs), the key cells in hepatic fibrosis, is unknown. Aerobic glycolysis despite the presence of oxygen is a characteristic of tumor cells. Thus, glucose transporter 1 (GLUT1) is highly expressed in hepatocellular carcinoma (HCC), where GLUT1 acts as a tumor promoter,…
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Zitierempfehlung
B Czech, D Valletta, M Müller, A Bosserhoff, C Hellerbrand (2014) Expression and function of glucose transporter 1 (GLUT1) expression in activated hepatic stellate cells. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1360859
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