CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Expression and function of methylthioadenosine phosphorylase (MTAP) in activated hepatic stellate
DOI 10.1055/s-0033-1360860
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Autor:innenB Czech, D Valletta, K Dettmer, M Müller, A Bosserhoff, P Oefner, C Hellerbrand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Regain methionine is essential for cellular metabolism and methylthioadenosine phosphorylase (MTAP), the rate-limiting enzyme in the methionine and adenine salvage pathway, catalyzes the phosphorylation of 5'-deoxy-5'-(methylthio)adenosine (MTA), which is a by-product of polyamine synthesis. The polyamine metabolic pathway has been implicated in the pathogenesis of chronic liver disease, and previous studies have sh…
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Zitierempfehlung
B Czech, D Valletta, K Dettmer, M Müller, A Bosserhoff, P Oefner, C Hellerbrand (2014) Expression and function of methylthioadenosine phosphorylase (MTAP) in activated hepatic stellate. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1360860
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