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Keratinocyte growth factor inhibits hepatic inflammation and fibrosis in murine models of hepatic injury

D Valletta, T Amann, B Czech, A Bosserhoff, C Hellerbrand · Zeitschrift für Gastroenterologie · Ausgabe 01/2014

DOI 10.1055/s-0033-1360869

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Autor:innenD Valletta, T Amann, B Czech, A Bosserhoff, C Hellerbrand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Keratinocyte growth factor (KGF) plays a pivotal role in regulating cell proliferation, migration, differentiation and survival, in response to injury and tissue repair. The activation of hepatic stellate cells (HSCs) is the key event of hepatic fibrosis, and we have previously shown that KGF expression is upregulated during the activation of HSCs. However, no data exist on the expression and function of KGF in chro…

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D Valletta, T Amann, B Czech, A Bosserhoff, C Hellerbrand (2014) Keratinocyte growth factor inhibits hepatic inflammation and fibrosis in murine models of hepatic injury. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1360869

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