CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Monocytes Affect Natural Killer cell Antiviral IFN-γ Production in HCV Infection via Inflammasome-mediated IL-18 Secretion
DOI 10.1055/s-0033-1360872
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Autor:innenJM Werner, E Serti, MA Chattergoon, AL Cox, V Lohmann, B Rehermann
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
IFN-γ production by Natural killer (NK) cells is attenuated in patients with chronic hepatitis C virus (HCV) infection. Here, we asked whether this impairment is NK cell-intrinsic or extrinsic. Hepatoma cells expressing luciferase-tagged subgenomic HCV replicons (Huh7/HCV-replicons) or their HCV-negative counterparts (Huh7) were co-cultured with NK cells in the presence or absence of other PBMC subsets. Antiviral ac…
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Zitierempfehlung
JM Werner, E Serti, MA Chattergoon, AL Cox, V Lohmann, B Rehermann (2014) Monocytes Affect Natural Killer cell Antiviral IFN-γ Production in HCV Infection via Inflammasome-mediated IL-18 Secretion. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1360872
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