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Simultaneous isolation of primary human hepatocytes and non-parenchymal liver cells for the establishment of functional co-culture and tissue engineering liver models

E Pfeiffer, V Kegel, B Burkhardt, D Seehofer, A Nüssler, G Damm · Zeitschrift für Gastroenterologie · Ausgabe 01/2014

DOI 10.1055/s-0033-1360879

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Autor:innenE Pfeiffer, V Kegel, B Burkhardt, D Seehofer, A Nüssler, G Damm
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Primary human hepatocytes (PHH) are parenchymal liver cells and represent ˜60 to 70% of total liver cells. Additionally non-parenchymal cells (NPC) like Kupffer cells (KC), Stellate cells (SC), cholangiocytes (CC) and sinusoidal endothelial cells (SEC) are present in the liver. NPC play a central role in many pathophysiologies of the liver, such as drug induced liver diseases, inflammation, liver fibrosis and cirrho…

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E Pfeiffer, V Kegel, B Burkhardt, D Seehofer, A Nüssler, G Damm (2014) Simultaneous isolation of primary human hepatocytes and non-parenchymal liver cells for the establishment of functional co-culture and tissue engineering liver models. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1360879

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