CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Synergism between Jnk1 and Jnk2 is a sine qua non condition for hepatic protection against toxicity
DOI 10.1055/s-0033-1360880
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Autor:innenFJ Cubero, G Zhao, W Hu, J Peng, YA Nevzorova, M Al Masaoudi, MV Boekschoten, M Muller, N Gassler, R Weiskirchen, C Trautwein
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Hepatocyte death, a feature of acute and chronic liver failure, is observable after acetoaminophen (APAP) poisoning in humans or LPS/GalN or CCl4-induced liver toxicity in mice. The activation of the c-Jun NH2 terminal kinase (JNK) intracellular signalling pathway during hepatocyte necrosis is a common molecular mechanism. In this context, the study of the shared functions of Jnk1 and Jnk2 in hepatocytes can be of u…
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Zitierempfehlung
FJ Cubero, G Zhao, W Hu, J Peng, YA Nevzorova, M Al Masaoudi, MV Boekschoten, M Muller, N Gassler, R Weiskirchen, C Trautwein (2014) Synergism between Jnk1 and Jnk2 is a sine qua non condition for hepatic protection against toxicity. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1360880
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