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Deficiency of group via Phospholipase A2 in OB/OB mice renders protection against hepatic steatosis by reduction of VLDL secretion and alteration of phospholipid fatty acid composition

X Deng, J Wang, S Tuma, G Schmitz, G Liebisch, W Stremmel, W Chamulitrat · Zeitschrift für Gastroenterologie · Ausgabe 01/2014

DOI 10.1055/s-0033-1360918

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Autor:innenX Deng, J Wang, S Tuma, G Schmitz, G Liebisch, W Stremmel, W Chamulitrat
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben

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Introduction: iPLA2β hydrolyzes fatty acyl bond at the sn-2 position of phospholipids (PL) recognized as a key process on homeostatic membrane metabolism. iPLA2β and its product lysophospholipids play a role in lipid synthesis and very low density lipoprotein (VLDL) assembly. Our previous study shows that global whole body deficiency of iPLA2β causes lower body weight as well as lower serum and hepatic lipids when c…

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X Deng, J Wang, S Tuma, G Schmitz, G Liebisch, W Stremmel, W Chamulitrat (2014) Deficiency of group via Phospholipase A2 in OB/OB mice renders protection against hepatic steatosis by reduction of VLDL secretion and alteration of phospholipid fatty acid composition. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1360918

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