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Genetically engineered hepatocytes as a capable application for in vitro liver cell systems

S Sperling, N Herzog, M Hansen, JH Küpper, D Seehofer, G Damm · Zeitschrift für Gastroenterologie · Ausgabe 01/2014

DOI 10.1055/s-0033-1360930

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Autor:innenS Sperling, N Herzog, M Hansen, JH Küpper, D Seehofer, G Damm
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2014
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: The use of primary human hepatocytes (PHH) in biomedical research is still considered as the gold standard. Their application possibilities encompass identifications of pathophysiological alterations and new biochemical pathways in liver diseases, e.g. steatosis. The main problems are the limited availability of liver tissue and donor variability. Therefore the development of alternative liver models has…

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S Sperling, N Herzog, M Hansen, JH Küpper, D Seehofer, G Damm (2014) Genetically engineered hepatocytes as a capable application for in vitro liver cell systems. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0033-1360930

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